My current project deals with the construction of a nutrient signaling model in the budding yeast S. cerevisiae. For more details, check out my blog post.
I have also made an interactive app to learn about mechanistic cell cycle models
Preprints
Jalihal, A.P., Degennaro, C., Jhuang, H-Y, Commins, N., Hamrick, S., Springer, M., 2021. Passive plasma membrane transporters play a critical role in perception of carbon availability in yeast. bioRxiv
Publications
Jalihal, A.P., Kraikivski, P, Murali, T.M., Tyson, J.J, 2020. Modeling and analysis of macronutrient signaling in budding yeast. Molecular Biology of the Cell
Pratapa, A., Jalihal, A.P., Law, J.N., Bharadwaj, A. and Murali, T.M., 2019. Benchmarking algorithms for gene regulatory network inference from single-cell transcriptomic data. Nature Methods, p.642926. pdf
Pratapa, A., Jalihal, A.P., Ravi, S.S. and Murali, T.M., 2018, August. Efficient Synthesis of Mutants Using Genetic Crosses. In Proceedings of the 2018 ACM International Conference on Bioinformatics, Computational Biology, and Health Informatics (pp. 53-62). ACM.